Dermatologists rely primarily on clinical examination in combination with histopathology to diagnose conditions; however, clinical examination alone might not be sufficient for accurate diagnosis and skin biopsies have associated morbidity. With continued technological advancement, there are emerging ancillary imaging technologies available to dermatologists to aid in diagnosis and management. This 2-part review article will discuss these emerging technologies including: digital photographic imaging, confocal microscopy, optical coherence tomography, and high-frequency ultrasound, as well as several additional modalities in development. In this first installment, the authors describe the breadth of technologies available and the science behind them. Then, in the second article, the authors discuss the applications and limitations of these technologies and future directions.Le texte complet de cet article est disponible en PDF.
Key words : confocal microscopy, dermatology, dermoscopy, digital photographic imaging, fluorescence imaging, high-frequency ultrasound, machine-based learning, multispectral optoacoustic tomography, optical coherence tomography, Raman spectroscopy
Abbreviations used : 3D, HFUS, MPT, MSOT, OCT, TBDP
| Funding sources: None.
| Conflicts of interest: Dr Schneider has no relevant conflicts to disclose. Dr Kohli has served as a subinvestigator for Estee Lauder, Unigen, Ferndale laboratories, Allergan, Chromaderm, Pfizer, Johnson & Johnson, and Bayer. Dr Hamzavi has served as research investigator for Estee Lauder, Unigen, Ferndale laboratories, Allergan, Bayer, Johnson & Johnson, and Incyte Corporation. Dr Council has served as consultant for MD Outlook and Medline Industries. Dr Rossi has served as consultant for Canfield Scientific Inc. Dr Ozog has served as investigator for MiRagen and Biofrontera, on the advisory board for Allergan, and was on the past medical board for DermOne.