Clinical examination is critical for the diagnosis and identification of response to treatment. It is fortunate that technologies are continuing to evolve, enabling augmentation of classical clinical examination with noninvasive imaging modalities. This article discusses emerging technologies with a focus on digital photographic imaging, confocal microscopy, optical coherence tomography, and high-frequency ultrasound, as well as several additional developing modalities. The most readily adopted technologies to date include total-body digital photography and dermoscopy, with some practitioners beginning to use confocal microscopy. In this article, applications and limitations are addressed. For a detailed discussion of the principles involved in these technologies, please refer to the first part of this review article.Le texte complet de cet article est disponible en PDF.
Key words : confocal microscopy, dermatology, dermoscopy, digital photographic imaging, fluorescence imaging, high-frequency ultrasound, machine-based learning, multispectral optoacoustic tomography, optical coherence tomography, Raman spectroscopy
Abbreviations used : 3D, BCC, CM, FCM, HFUS, MBL, MPT, MSOT, NMSC, OCT, RCM, SCC, TBDP
| Funding sources: None.
| Conflicts of interest: Dr Schneider has no relevant conflicts to disclose. Dr Kohli has served as a subinvestigator for Estee Lauder, Unigen, Ferndale laboratories, Allergan, Chromaderm, Pfizer, Johnson & Johnson, and Bayer. Dr Hamzavi has served as research investigator for Estee Lauder, Unigen, Ferndale laboratories, Allergan, Bayer, Johnson & Johnson, and Incyte Corporation. Dr Council has served as consultant for MD Outlook and Medline Industries. Dr Rossi has served as consultant for Canfield Scientific Inc. Dr Ozog has served as investigator for MiRagen and Biofrontera, on the advisory board for Allergan, and was on the past medical board for DermOne.