Peripheral arterial disease of the lower limbs in asymptomatic diabetic patients: Prevalence and determining factors - 21/03/19
Résumé |
Background |
Peripheral arterial disease (PAD) of the lower limbs is an important predictor of cardiovascular disease; however it's still underdiagnosed over asymptomatic diabetic patients, free of cardiovascular disease.
Purpose |
Determining the prevalence and risk factors for PAD in an asymptomatic population of diabetic patients at low or intermediate risk factors of cardiovascular disease, with a free history of cardiovascular disease.
Methodology |
This was a prospective study conducted over 14 months period from November 2017 to January 2018. A total of 309 diabetic patients were included from two diabetes centers. PAD was defined as an ankle-brachial index (ABI) less than 0,9.
Results |
Among the 309 patients, the ankle-brachial index (ABI) was <0.9 in 98 (31,71%) patients considered to have PAD. The ABI was >1.3 in 36 (11,35%) patients who had suspected mediacalcosis.
The average age of the PAD population was 56.2 years. Female gender predominated (57%). The mean duration of diabetes was 11 yeras: 80% type II Diabetes.
PAD of the lower limbs was mild in 26 patients (26,53%) moderate in 49 (50%) and severe in 23 (23,46%).
Duplex Doppler commonly showed lesions of the femoral and tibial arteries.
Factors associated with PAD were advanced age (P<0.0001), age of diabetes>6 years (P<0.0001), uncontrolled diabetes as assessed by HbA1c levels>7% (P<0), 0001) and elevated fasting glucose levels (P=0.039), Hypertension (P<0.0001) and dyslipidemia (P<0.0001).
For mediacalcosis, male gender was the only factor identified.
Conclusion |
Primary prevention outpatient screening of asymptomatic diabetic patients with lower or intermediate cardiovascular risk can identify numerous patients with PAD. Advanced age, a mean duration of diabetes over 6years, uncontrolled diabetes, hypertension, and dyslipidemia were predictive factors for diabetic PAD of the lower limbs in our population.
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Vol 11 - N° 2
P. 188 - avril 2019 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.