The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis - 12/04/19
Abstract |
Background |
Dermoscopy is a noninvasive technique for the diagnosis of skin lesions. Its accuracy for basal cell carcinoma (BCC) has not been systematically studied.
Objective |
We sought to systematically investigate the accuracy of dermoscopy for the diagnosis of BCC compared with examination with the naked eye.
Methods |
A systematic review of studies reporting the accuracy of naked eye examination and dermoscopy for the diagnosis of BCC was conducted. A meta-analysis for sensitivity and specificity was performed using a bivariate mixed-effects logistic regression modeling framework.
Results |
Seventeen studies were identified. The pooled sensitivity and specificity of dermoscopy for the diagnosis of BCC were 91.2% and 95%, respectively. In studies comparing test performance, adding dermoscopy to naked eye examination improved sensitivity from 66.9% to 85% (P = .0001) and specificity from 97.2% to 98.2% (P = .006). The sensitivity and specificity of dermoscopy were higher for pigmented than nonpigmented BCC. Sensitivity increased when dermoscopy was performed by experts and when the diagnosis was based on in-person dermoscopy as opposed to dermoscopic photographs.
Limitations |
Significant heterogeneity among studies with a medium-to-high risk of bias.
Conclusion |
Dermoscopy is a sensitive and specific add-on tool for the diagnosis of BCC. It is especially valuable for pigmented BCC.
Le texte complet de cet article est disponible en PDF.Key words : dermoscopy, dermatoscopy, basal cell carcinoma
Plan
Dr Reiter and Ms Mimouni contributed equally to this article. |
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Funding sources: None. |
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Conflicts of interest: None disclosed. |
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Reprints not available from the authors. |
Vol 80 - N° 5
P. 1380-1388 - mai 2019 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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