Sexual rights (SR) are grounded in universal human rights, however, despite recent gains in equality, many lesbian, gay and bisexual (LGB) individuals and couples still face discrimination. The aim of this study was to analyze the level of agreement of the Italian general population with the sexual rights of LGB people and couples. A further aim was to better understand the sociodemographic characteristics associated with the different level of recognition of the LGB SR. An online anonymous questionnaire was carried out to collect demographic data and information about the level of agreement/disagreement, coded on a 6-point likert scale, with statements regarding the rights of heterosexual and LGB people. One thousand and seven out people who had access to the questionnaire met the inclusion criteria. The sample showed overall moderate-high levels of agreement with SR of LGB men and women in high percentages, and more than 85.0% declared themselves in favor of the right, for the LGB people, to have a satisfactory sexuality. The participants showed a lower degree of agreement in relation to the adoption of children by LGB couples. The most discriminated against are bisexuals of both sexes. With respect to sociodemographic variables, being female, graduated, was observed as related to a greater recognition of the rights considered. Being a believer and to a greater extent being a believer churchgoer has been observed as a predictor of lesser recognition of such LGB rights. Data shows how focusing efforts where possible on the knowledge of sexual orientation to overcome stereotypes based on ignorance is crucial for LGB sexual and general health.