Clinical and psychological characteristics of patients with globus - 29/09/19
, Noëlle Girault-Lidvan c, Maria Hejnar d, Florence Mary b, Gheorges Airinei b, Robert Benamouzig bBienvenue sur EM-consulte, la référence des professionnels de santé.
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Highlights |
• | Globus is a frequent pathology of unknown origin. |
• | The psychological factors are frequently underlined in globus patients as well in patients with other functional digestive disorders. |
• | Using the Minnesota Multiphasic Personality Inventory 2, the present study shows abnormal psychological profile in the globus patients as compared to other patients with chronic functional digestive disorders. |
• | Moreover, half of the globus patients have abnormal high hysteria score. These patients have also higher values for most personnality clinical scales. |
Summary |
Background/aims |
Psychological factors are involved in many functional gastrointestinal disorders including globus. The aim of the present study was to assess the clinical and psychological correlates associated with globus.
Patients and methods |
707 patients (69% female, 45.2 ± 16.5 years, BMI 27.2 ± 11.7 kg/m2) filled an MMPI-2 questionnaire and a standard Rome III clinical questionnaire and were included in this cross sectional study. Data analysis was performed using a univariate analysis and a multivariate logistic regression with a backwards selection procedure on significant scales after a univariate analysis.
Results |
140 patients (20%) reported suffering from globus. Globus appeared to be associated with older age (P = 0.001; OR = 1.022; 95% CI = [1.009–1.035]), increased BMI (P = 0.007; OR = 1.029; 95% CI = [1.008–1.051]), higher prevalence of regurgitations (P = 0.008; OR = 2.189; 95% CI = [1.228–3.902]), heartburn (P = 0.001 OR = 2.227; 95% CI = [1.406–3.530]), dysphagia (P < 0.001; OR = 2.399; 95% CI = [1.500–3.837]), epigastric pain (P < 0.001; OR = 3.768; 95% CI = [1.880–7.552]) and nonspecific dyspepsia (P = 0.018; OR = 1.786; 95% CI = [1.106–2.881]), and a higher score of hysteria (P = 0.008 OR = 1.034; 95% CI = [1.009–1.059]). By comparison with patients who reported globus and scores of hysteria in the normal range (n = 73), patients complaining of globus associated with high scores of hysteria (n = 67) have high scores of hypochondriasis (P < 0.001; OR = 1.235; 95% CI = [1.142–1.336]), high levels of Psychopathic deviate (P = 0.005; OR = 1.091; 95% CI = [1.026–1.161]) and a higher, but not significant, prevalence of complaints of regurgitation (P = 0.052; OR = 4.022; 95% CI = [0.989–16.351]).
Conclusion |
Approximately 50% of the patients complaining of globus have a high score of hysteria associated with other personality disorders, and complain more frequently of regurgitation than other patients complaining of globus. These results tend to confirm that globus has a strong, although not systematic, connections with some specific personality disorders.
Le texte complet de cet article est disponible en PDF.Keywords : Globus, Hysteria, Hypochondriasis, MMPI-2
Plan
Vol 43 - N° 5
P. 614-622 - octobre 2019 Retour au numéro
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