“Adaptative endovascular strategy to the CloT MRI in large intracranial vessel occlusion” (VECTOR): Study protocol of a randomized control trial - 26/11/19

Doi : 10.1016/j.neurad.2019.11.001

Kevin Janot ^a,⁎ , François Zhu ^b, Basile Kerleroux ^a, Grégoire Boulouis ^c, Eimad Shotar ^d, Kevin Premat ^d, François Eugene ^e, Cyril Dargazanli ^f, Vanessa Chalumeau ^g, Vincent L’Allinec ^h, Wagih Benhassen ^c, Gaultier Marnat ⁱ, Anthony Lebras ^j, Lili Detraz ^k, Julien Ognard ^l, Thomas Personnic ^m, Cyril Chivot ⁿ, Matteo Cappucci ^o, Géraud Forestier ^p, Sébastien Soize ^q, Frédéric Bourdain ^r, Arthuro Consoli ^s, Julien Labreuche ^t, Hubert Desal ^k, Bertrand Lapergue ^s, Aymeric Rouchaud ^p,^{^{1
Both authors contribute equally to this work.}}, Romain Bourcier ^k,^{^{1
Both authors contribute equally to this work.}}
JENI Research Collaboration
^a Department of Neuroradiology, University Hospital of Tours, 2, boulevard Tonnellé, 37000 Tours, France
^b University Hospital of Nancy, France
^c Saint-Anne Hospital, Paris, France
^d La Pitie-Salpetrière Hospital, Paris, France
^e University Hospital of Rennes, Rennes, France
^f University Hospital of Montpellier, Montpellier, France
^g Bicêtre Hospital, Le Kremlin-Bicêtre, France
^h University Hospital of Angers, Angers, France
ⁱ University Hospital of Bordeaux, Bordeaux, France
^j Regional Hospital of Vannes, Vannes, France
^k University Hospital of Nantes, Nantes, France
^l University Hospital of Brest, Brest, France
^m University Hospital of Lille, Lille, France
ⁿ University Hospital of Amiens, Amiens, France
^o University Hospital of Lyon, Lyon, France
^p University Hospital of Limoges, Limoges, France
^q University Hospital of Reims, Reims, France
^r Regional Hospital of Bayonne, Bayonne, France
^s Foch Hospital, Suresnes, France
^t Department of Biostatistics, University Hospital of Lille, Lille, France

^⁎Corresponding author.

Sous presse. Épreuves corrigées par l'auteur. Disponible en ligne depuis le Tuesday 26 November 2019
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Résumé

Graphical abstract

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Highlights

•	A correlation between the susceptibility vessel sign (SVS) and red thrombi has been identified in MRI.
•	We hypothesized that the Embotrap allow better retrieving of SVS+ thrombi.
•	The VECTOR trial is a multicenter, prospective and randomized study designed to compare a first line strategy combining Embotrap added to contact aspiration (CA) versus CA alone in patients with SVS+ occlusions.

Le texte complet de cet article est disponible en PDF.

Abstract

A correlation between the susceptibility vessel sign (SVS) and red thrombi has been identified in MRI. We hypothesized that the Embotrap allow better retrieving of SVS+ thrombi. The AdaptatiVe Endovascular strategy to the CloT MRI in large intracranial vessel Occlusion (VECTOR) trial is a multicenter, prospective and randomized study designed to compare a first-line strategy combining Embotrap added to contact aspiration (CA) versus CA alone in patients with SVS+ occlusions.

Le texte complet de cet article est disponible en PDF.

Keywords : Clot, MRI, Stroke, Mechanical thrombectomy