It is common sense in the homeopathic community that treating patients with diverse infections generates satisfactory clinical responses by enhancing the immune response. But experimental laboratory studies show exactly what happens in each case and how the immune response dynamically adjusts to the conditions of the infection in question. In this article, we aim to describe a brief review of the latest studies conducted by our group on animal and cellular models on immune cell activity against different infectious agents following treatment with specific homeopathic preparations. The studies dealt with infections induced by bacteria, fungi and protozoa.