There are currently no official government strategies to formally investigate or use complementary and alternative therapies (CAM) in the treatment and/or prevention of human infectious diseases. This a particularly striking omission when the global threat of antimicrobial resistance requires consideration of all potential strategies to reduce the use of antibiotics. Additionally, observational studies have shown that CAM therapies can have lower antibiotic prescription rates than conventional healthcare approaches. The aim of this study was to create an overview of the currently available clinical research evidence assessing the effectiveness and safety of homeopathy in the context of antibiotic usage, for named human infectious diseases.