Anti-inflammatory effects of Rhodiola rosea L.: A review - 30/11/19

Doi : 10.1016/j.biopha.2019.109552

Wei-ling Pu ^a,^b, Meng-ying Zhang ^a,^c, Ru-yu Bai ^a,^c, Li-kang Sun ^c,^{^{1
These authors contributed equally to this work.},}⁎ , Wen-hua Li ^d,^{^{1
These authors contributed equally to this work.},}⁎ , Ying-li Yu ^a,^b, Yue Zhang ^a,^b, Lei Song ^a,^b, Zhao-xin Wang ^a,^b, Yan-fei Peng ^c, Hong Shi ^a,^b, Kun Zhou ^a,^b,^e, Tian-xiang Li ^f
^a Institute of Traditional Chinese Medicine, Tianjin University of Traditional ChineseMedicine, Tianjin 301617, China
^b Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin University ofTraditional Chinese Medicine, Tianjin 301617, China
^c School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine,Tianjin 301617, China
^d College of Medicine, Xizang Minzu University (Tibetan National University), Xianyang 712082, Shaanxi, China
^e Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
^f College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China

^⁎Correspondence author.

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Abstract

Rhodiola rosea L., a worldwide botanical adaptogen, has been confirmed to possess protective effects of inflammatory injury for many diseases, including cardiovascular diseases, neurodegenerative diseases, diabetes, sepsis, and cancer. This paper is to review the recent clinical and experimental researches about the anti-inflammatory effects and the related mechanisms of Rhodiola rosea L. extracts, preparations, and the active compounds. From the collected information reviewed, this paper will provide the theoretical basis for its clinical application, and provide the evidences or guidance for future studies and medicinal exploitations of Rhodiola rosea L.

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Abbreviation : ACI, ACS, BUN, CHD, CK-MB, CRP, DN, FBG, HAMD, HbA1C, HDL, LAD, LDL, LVEF, LVEDD, LVESD, LVPWTD, LDH, MCAO, MDA, MI, PAH, SAP, SDS, t-PA, UAP, VEGF, 6-MWT

Keywords : Rhodiola rosea L., Salidroside, Sofren injection, Anti-Inflammation

Plan

Introduction

Cardiovascular disease

Neurodegenerative diseases

Diabetes

Cancer

Other inflammatory diseases

Conclusion

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Vol 121

Article 109552- janvier 2020 Retour au numéro

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Anti-inflammatory effects of Rhodiola rosea L.: A review - 30/11/19

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