Everyday practice of cardioversion safety on apixaban: The French AMPER-AF cardioversion study - 06/01/20
, R. Garcia 2, J. Mansourati 3, J. Taieb 4, E. Gandjbackh 5, A. Dompnier 6, H. Gorka 7, N. Zannad 8, A. Da Costa 9, F. Sacher 10, F. Jourda 11, S. Fromentin 12, S. Cheggour 13, F. Georger 14, A. Milhem 15
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Résumé |
Purpose |
To evaluate thromboembolic complications in patients taking apixaban and undergoing a cardioversion procedure in everyday clinical practice.
Methods |
It is a multicenter, observational, prospective study of patients with non-valvular atrial fibrillation (AF) undergoing cardioversion (electric or medical). Eligible patients had been taking apixaban (2.5 or 5mg twice daily) for ≥3 weeks before the procedure, and were followed for 30 days afterwards.
Results |
A total of 278 patients (68 [61,76] years, 71% male, mean CHA2DS2-VASc score 2, mean HAS BLED score 2) were enrolled at 25 academic/non-academic centres in France; 248 patients (89%) were receiving apixaban 10mg/day and 29 (11%) 5mg/day. The most prevalent concomitant disorders were hypertension (50% of patients) and diabetes (15%). The mean creatinine clearance (Cockroft−Gault) was 81±34mL/min. The majority of patients had an electric cardioversion (264, 95%)and 14 patients (5%) received amiodarone only. Cardioversion was a planned procedure in the most of cases (97%). Sixty-seven patients (24%) had a transeophageal echocardiogram before procedure. There were no reported thromboembolic events.
Conclusion |
These observational data of patients on apixaban undergoing cardiversion in everyday practice show no thromboembolic events on a follow-up of 30 days.
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Vol 12 - N° 1
P. 117 - janvier 2020 Retour au numéro
Article précédent
- Acute and long-term ablation results of extra pulmonary vein drivers detected by ultra high density mapping on top of PVI in persistent AF
- B. Enache, D.G. Latcu, K. Hasni, S. Bun, N. Saoudi
- Incidence, clinical features, and long-term outcomes of new-onset atrial fibrillation in the intensive care unit: A prospective observational study
- M. Labbaoui, D. Doyen, F. Squara, E. Ferrari
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