Factors associated with high blood pressure in a group of women with a history of pre-eclampsia in Yaoundé in Sub-Saharan Africa - 06/01/20
Résumé |
Background |
Women with pre-eclampsia are at risk of developing cardiovascular diseases in future.
Purpose |
To determine the factors associated with hypertension in a group of women who had pre-eclampsia over the last five years in Yaoundé, urban city Cameroon.
Methods |
From November 2017 to June 2018, we conducted a case control study in two major obstetrical and gynaecologic units of Yaoundé. Were included all woman aged 18 to 45 with documented diagnosis of preeclampsia from 2011 to 2016. We performed a consecutive sampling, patients eligible were called, and upon their informed consent, they were screened for hypertension according to WHO guidelines. We performed a complete physical examination, and assessed cardiovascular risk factors through past medical history. In both groups, blood pressure and anthropometric measurements were measured using standard and validated procedures. Data were analysed using SPSS software version 23. A P-value<0.05 was considered statistically significant.
Results |
Ninety-two women were included in the study (30 cases and 62 controls). The mean age of the study participants was 7.43±4.4 for cases and 30.45±6.9 for controls with extreme of 18 and 45 years. In univariate model, risk factors found were: age range between 30 and 45 years at the time of the study (P-value:<0.001), being married (P-value: 0.024), gravidity≥5 (P-value:<0.001) or parity≥5 (P-value:<0.001), gestational age between 28 and 37 weeks (P-value: 0.004) or a 24h proteinuria≥5g/L by the time of the diagnosis of preeclampsia (P-value: 0.035), and family history of diabetes (P-value: 0.001). After multivariate analysis model, only parity (P-value: 0.008) and family history of diabetes (P-value: 0.003) persisted.
Conclusion |
This study provides baseline informations and a start to a debate on the potential factors associated with hypertension after pre-eclampsia.
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Vol 12 - N° 1
P. 139 - janvier 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.