An analysis of differences in risk factors, clinical features, Angiographic profiles and outcomes in young versus older adults with myocardial infarction (Morrocan experience) - 06/01/20
Résumé |
Background |
The prevalence of Coronary heart disease (CHD) is continuously increasing. There is a lack of clinical data concerning Myocardial infarction (MI) in “young” individuals.
Purpose |
This study was designed to evaluate the differences in risk factors, clinical characteristics, angiographic findings and outcomes between young and older patients with MI.
Methods |
This study contained both retrospective and prospective components and was fully conducted within the Department of Cardiology at the University Hospital Center of Casablanca between December 2016 and March 2018. This study included patients with MI who underwent coronary angiography aged less than 45 years (group I), compared to the control group (group II) which included patients older than 55 years.
Results |
Overall, the study included 350 patient of which 110 were≤45 years of age. The mean age of the younger cohort was 39.57 vs. 66.25 years. In both groups, the male sex was more common. In group I, Smoking was the most frequent risk factor (60.7% vs. 35.8%; P<0.001). Hypertension was significantly more common in group II (59.7% vs. 32.4%; P=0.02). Family history of CHD was found mostly in group I (35,4% vs. 7,6%; P<0.001). No statistically significant differences were observed between the two groups with regards to the presence of diabetes mellitus, obesity and dyslipidemia. In younger patients, 53% had single vessel disease vs. 23% in group II. Multi-vessel disease was more common in older patients (75% in group II vs. 42% in group I; P<0.001). Normal angiography findings were observed in 5% of cases in group I versus 2% in group II. Younger patients had also better in-hospital outcomes (1% in group I vs. 6% in group II)
Conclusion |
Myocardial infarction in young adults presents several characteristics, with an identifiable risk factor profile, measurable angiographic findings and better outcomes. Screening for Smoking should be strongly considered as early as possible.
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Vol 12 - N° 1
P. 24 - janvier 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.