SYNTAX score as predictor of one-year mortality in patients with NSTE-ACS - 06/01/20
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Résumé |
Background |
The syntax score have been used as surrogate end-points for evaluating the complexity of coronary lesions in stable coronary artery disease, but their predictive value in acute coronary artery disease is inconclusive.
Purpose |
The aim of this study was to evaluate the ability of the syntax score to predict one-year mortality in patients with NSTE-ACS.
Methods |
Patients admitted for NSTE-ACS and indication for coronary angiography were prospectively evaluated. The Syntax score was calculated. A ROC curve was developed to define the Syntax score cut-off that best predicts one-year cardiovascular mortality.
Results |
A total of 296 patients were evaluated: mean age was 62±12 years and 58% were male. The cardiovascular one-year mortality was 5.4% (16 patients). The syntax score in these patients was significantly higher (31.3±13.3 vs. 13.1±13.2; p<10−3). Syntax score ≥20 showed a sensitivity of 87.5%, specificity of 75.7%. The area under the ROC curve was 0.84 (95% confidence interval of 0.76–0.93) (Fig. 1).
Conclusions |
Syntax score ≥20 had a good specificity to predict one-year mortality in patients with NSTE-ACS. Its measurement may be incorporated to help in the assessment and stratification of NSTE-ACS patients.
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Vol 12 - N° 1
P. 25 - janvier 2020 Retour au numéro
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