Cardiorenal syndrome (CRS) is the association of heart failure (HF) and renal failure (RF). This association is poor in terms of prognosis.

To determine the correlation between glomerular filtration rate (GFR) and left ventricular ejection fraction (LVEF), and their impact on death.

This cross-sectional study, by document analysis, was conducted from January 2016 to December 2017 in the departments of cardiology and nephrology at University Hospital of Brazzaville. We had included the patients with association HF and RF.

One hundred and eighty-six patients, 105 men (56.5%) were included. The mean age was 58±15.5 years (range: 17 to 90 years). The risk factors were: hypertension (n=128, 68.8%), diabetes (n=56, 30%) and alcoholism (n=23, 12.4%). At admission, the mean serum creatinine level was 47.2±55.5mg/L (range 16 to 136) and the mean GFR was 24.5±22.8ml/min (range: 2.1 and 100). In echocardiography, mean LVEF was 47.8±18.2% (range: 22 to 87). LVEF<40% was reported in 57 cases (30.6%). No correlation between the level of GFR and LVEF (r=0.026) was detected. Death was recorded in 18 cases (8%). In the bivariate analysis, death was associated with serum creatinine >100mg/L (n=9, 50%, OR 11.8, CI95% 4–35, P<0.0001) and CRS due to systemic disease. (n=13, 72%, OR 1.53, CI95%0.52–4.51, P=0.43). In logistic regression analysis, only serum creatinine>100mg/L was independent determinant of death (OR 10.7, 95% CI 2.3–44, P=0.001).

The prognosis of CRS is poor because the direct relation of blood creatinine level and death. Indeed, due to the limited access to dialysis in our country, the overall care of patients remains difficult. The extension and implantation of dialysis centers in our country remain the major challenges.