The incidence of acidosis in term and healthy neonates and the consequences on their neurodevelopment are poorly studied. The aim of our study was to assess neurodevelopmental outcome at 24 months by a parental questionnaire (ASQ, Ages and Stages Questionnaires) of healthy infants with a pH≤7 or/and hyperlactacidemia ≥7mmol/l on umbilical arterial blood and to compare their neurodevelopmental outcome with control group.
During the 29 months of the study, we retrospectively included all children who had a pH≤7 and/or lactates ≥7mmol/l on umbilical artery (UA) cord with good clinical adaptation. We also included a control group of term newborns with “normal” gases at birth. Age and stage questionnaires were sent to parents at 24 months of age.
Among the 9016 births during the study, 7.1 % babies had an UA pH<ou=7 and/or lactates≥7mmol/l. We have received 264 questionnaires in the acidosis group and 234 in the control group. The ASQ was considered as non-optimal for 32.2 % and 36.3 % of respondent respectively in the acidosis and control group without any significant difference (p=0.382). After matching on gestational age and sex there was also no significant difference in the rate of non-optimal ASQ. The percentage of abnormal communication was significantly higher in the control group (19.7 % versus 11.4%, p=0.015).
Isolated umbilical cord abnormalities in term or near-term newborns with good adaptation do not appear to have a long-term impact on development. These results are rather reassuring and the absence of specific follow-up for these children seems reasonable.
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Vol 3 - N° 1P. 103-104 - mars 2020 Retour au numéro
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