Prevalence of Rathke cleft cysts in children on magnetic resonance imaging - 25/03/20
Abstract |
Purpose |
The purposes of this study were to estimate the prevalence of Rathke cleft cysts (RCC) in a pediatric population on brain MRI, to describe their appearance, and to estimate interobserver agreement in the detection of RCC.
Materials and methods |
The brain MRI examinations of 460 children were retrospectively reviewed by two radiologists for the presence of RCC. There were 223 boys and 237 girls with a mean age of 8.8±4.3 (standard deviation [SD]) years (range: 0.1–14.9 years). When present, RCC were analyzed with respect to internal contain and further classified as serous RCC (i.e., high signal on T2-weighted sequences and iso or low signal on T1-weighted sequences) or mucosal RCC (i.e., low signal on T2-weighted sequences and high or iso signal on T1-weighted sequences). Cohen's Kappa coefficient was used to estimate interobserver agreement between the interpretations performed by the two radiologists for the presence of RCC.
Results |
A total of 14 children had a RCC present on brain MRI, yielding a prevalence of 3.04% (14/460); of these, 3/14 RCCs (21%) were of serous type and 11/14 (79%) were of mucosal type. Interobserver agreement for the presence of RCC was strong (Kappa=0.85; 95% CI: 0.70; 0.99).
Conclusion |
The results of our study suggest that the prevalence of RCC in children is greater than previously described.
Le texte complet de cet article est disponible en PDF.Keywords : Pituitary gland, Cyst, Child, Prevalence, Magnetic resonance imaging (MRI)
Plan
Vol 101 - N° 4
P. 209-215 - avril 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.