Acne vulgaris and risk of depression and anxiety: A meta-analytic review - 23/07/20
, Robert Rosenthal, PhD b, Rick Lin, DO, MPH c, d, Soham Chaudhari, DO c, d, Misaki N. Natsuaki, PhD bAbstract |
Background |
Several studies have shown an association of acne vulgaris with depression and anxiety, but a quantitative review has not yet been conducted.
Objective |
We sought to conduct a systematic review and meta-analysis that elucidates the association of acne vulgaris with depression and anxiety.
Methods |
A systematic review and meta-analysis of literature published before October 1, 2019 from the PubMed, PsycINFO, MEDLINE, and Cochrane databases was conducted. We used a metaanalytic approach to perform a random effects analysis comparing individuals with and without acne. Subgroup analyses between studies included age, study setting, and geographic region.
Results |
Forty-two studies were included. We found a significant association of acne vulgaris with depression (r = 0.22 [95% confidence interval 0.17-0.26, P < .00001]) and anxiety (r = 0.25 [95% confidence interval 0.19-0.31, P < .00001]). Subgroup analyses and comparisons showed moderating influences based on factors including age, study setting, and geographic region.
Limitations |
Inconsistency between publications regarding acne and outcome ascertainment, data reporting, and studies with no control group posed considerable barriers to synthesizing all available published literature.
Conclusions |
Because of an increased risk for depression and anxiety, clinicians should pursue aggressive treatment of acne and consider psychiatric screening or referrals.
Le texte complet de cet article est disponible en PDF.Key words : acne, acne vulgaris, adolescence, anxiety, depression, meta-analysis, meta-analytic review, psychiatric morbidity
Plan
| Funding sources: None. |
|
| Conflicts of interest: None declared. |
|
| IRB approval: Not applicable. |
Vol 83 - N° 2
P. 532-541 - août 2020 Retour au numéro
Article précédent
- Differing biologic behaviors of desmoplastic melanoma subtypes: Insights based on histopathologic, immunohistochemical, and genetic analyses
- Kevin Yang, Meera Mahalingam
- The prevalence and odds of anxiety and depression in children and adults with hidradenitis suppurativa: Systematic review and meta-analysis
- Isabelle Jalenques, Laura Ciortianu, Bruno Pereira, Michel D'Incan, Sophie Lauron, Fabien Rondepierre
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?