The prevalence and odds of anxiety and depression in children and adults with hidradenitis suppurativa: Systematic review and meta-analysis - 23/07/20
Abstract |
Background |
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. Previous studies have yielded divergent results on the prevalence of depression and anxiety in patients with HS.
Objective |
The aim of this meta-analysis was to provide a pooled estimate of the prevalence and odds of depression/anxiety in patients with HS.
Methods |
Search for and extraction of relevant literature without restrictions from 5 databases (Cochrane Database, EMBASE, PubMed, PsycINFO, Science Direct) were performed. Pooled meta-analyses were made by using random-effects models.
Results |
Meta-analyses of 28 studies of depression in HS and 12 of anxiety showed a prevalence of 21% (95% CI [17-25]) of depression and 12% (95% CI [6-17]) of anxiety in patients with HS, with very wide variations in both cases. Analysis of case-control studies showed an association between depression and HS (odds ratio, 1.99 95% CI [1.63-2.43]) and between anxiety and HS (odds ratio, 1.97 95% CI [1.65-2.35]).
Limitations |
The results of this meta-analysis are conditioned by the limitations of the studies included and by differences in patient populations, methodologic approach, and data available.
Conclusion |
Patients with HS have a high burden of depression and anxiety. Our results show that clinicians need to be vigilant for the presence of depression or anxiety and to refer patients when appropriate.
Le texte complet de cet article est disponible en PDF.Key words : anxiety, depression, hidradenitis suppurativa, meta-analysis, systematic review
Abbreviations used : CI, EC, HS, OR
Plan
Funding sources: None. |
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Conflicts of interest: None disclosed. |
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IRB approval status: Not applicable. |
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Reprints not available from the authors. |
Vol 83 - N° 2
P. 542-553 - août 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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