Splenial Lesions in Benign Convulsions With Gastroenteritis Associated With Rotavirus Infection - 23/07/20
Abstract |
Objective |
To investigate clinical risk factors for acute magnetic resonance imaging (MRI) abnormalities in patients with benign convulsions with mild gastroenteritis or benign infantile epilepsy.
Study design |
We investigated clinical and diffusion-weighted imaging findings in 32 patients with benign convulsions with mild gastroenteritis and 22 patients with benign infantile epilepsy who underwent MRI within seven days of seizure onset between 2010 and 2015.
Results |
Diffusion-weighted imaging showed signal hyperintensity in the splenium of the corpus callosum in seven patients with benign convulsions with mild gastroenteritis, but no abnormalities in patients with benign infantile epilepsy. Patients with benign convulsions with mild gastroenteritis with splenial lesions showed a higher rate of rotavirus detection from feces (P = 0.006), higher serum level of C-reactive protein (P = 0.04), and shorter interval between seizure onset and MRI (P = 0.002) than patients with benign convulsions with mild gastroenteritis without splenial lesions. Multivariate analysis revealed rotavirus infection as a significant risk factor for splenial lesions on diffusion-weighted imaging in patients with benign convulsions with mild gastroenteritis (P = 0.02).
Conclusions |
Splenial lesions are often seen during acute period in patients with benign convulsions with mild gastroenteritis. Rotavirus infection is a risk factor for splenial lesions in patients with benign convulsions with mild gastroenteritis, suggesting the role of rotavirus to cause edema in the corpus callosum. From our observations, benign convulsions with mild gastroenteritis with a splenial lesion on diffusion-weighted imaging suggests good outcomes, and extensive evaluation of these patients may be unnecessary.
Le texte complet de cet article est disponible en PDF.Keywords : Diffusion-weighted imaging, Benign convulsions with mild gastroenteritis, Benign infantile epilepsy, Mild encephalitis or encephalopathy with reversible splenial lesion, Rotavirus infection
Plan
Conflict of interest and disclosure: The authors have no conflicts of interest to disclose. |
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Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. |
Vol 109
P. 79-84 - août 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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