Short duration of post-amputation antibiotic therapy in diabetic foot patients with total resection of osteomyelitis - 28/07/20
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Highlights |
• | We evaluated the long-term effectiveness of short-duration post-amputation antibiotic therapy in diabetic patients with total resection of osteomyelitis assessed by sterile bone bacteriological samples obtained from resection margins. |
• | The endpoint was the absence of osteomyelitis relapse at 6 months, defined as recurrence of osteomyelitis with the need for surgical revision and/or new bone antibiotic therapy. |
• | Of the 15 patients included in our study, 80% were cured without recurrence of osteomyelitis at 6 months, with a mean duration of post-surgical antibiotic therapy of 8.3±5.9 days. |
• | In a small, real-life population, we showed that a short duration of post-amputation antibiotic therapy in diabetic patients is effective. |
Abstract |
Background |
Short duration of post-amputation antibiotic therapy (2–5 days) is recommended in patients with diabetic foot osteomyelitis after total resection of infected bone tissue.
Objective |
To evaluate the long-term effectiveness of short-duration post-amputation antibiotic therapy in diabetic patients with total resection of osteomyelitis assessed by sterile bone bacteriological samples obtained from the resection margin.
Methods |
The endpoint was the absence of osteomyelitis relapse at 6 months, defined as recurrence of osteomyelitis with the need for surgical revision and/or new bone antibiotic therapy.
Results |
Among 15 patients included, 12 (80%) were cured without recurrence of osteomyelitis at 6 months, with a mean duration of antibiotic therapy of 8.3±5.9 days post surgery. This result is comparable to literature data, while all of them reported longer duration of antibiotic therapy and/or shorter follow-up.
Conclusion |
Short duration of post-amputation antibiotic therapy in diabetic patients with sterile bacteriological samples obtained from resection margin seems effective.
Le texte complet de cet article est disponible en PDF.Keywords : Diabetic foot osteomyelitis, Diabetes, Osteomyelitis, Antibiotic duration
Plan
Vol 50 - N° 5
P. 433-435 - août 2020 Retour au numéro
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