Initial validation of the product of the signs global assessment and body surface area in atopic dermatitis - 27/08/20
Cet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Abstract |
Background |
Current valid instruments that measure the signs of atopic dermatitis in clinical trials may not be suitable for clinical practice because of their complexity. The product of a clinician-derived 5-point signs global assessment and body surface area (SGA × BSA) may represent a simple approach to quickly assess the severity of signs in patients with atopic dermatitis in clinical practice.
Objectives |
Evaluate the basic measurement properties of the SGA × BSA.
Methods |
Retrospective chart review of patients with atopic dermatitis treated in an outpatient dermatology clinic at Oregon Health & Science University from 2015 to 2018 who had a recorded BSA and SGA.
Results |
We identified 138 patients completing 325 clinic visits. SGA × BSA demonstrated strong and statistically significant (P < .001) correlations with the Eczema Area and Severity Index (r = 0.91, n = 19), average daily pruritus (r = 0.71, n = 177), patient global assessment (r = 0.74, n = 170), and a derived global scale composed of the average of 4 signs rated between 0 and 3 (r = 0.77, n = 282). Acceptability, responsiveness, and floor or ceiling effects of the measure were deemed adequate. Severity banding was maximized at 1, 21, and 87 (κ = 0.4902).
Limitations |
The patient cohort was gathered exclusively from a tertiary care clinic setting in the Pacific Northwest and lacked ethnic diversity.
Conclusions |
The results from this study suggest that SGA × BSA is a valid and feasible instrument for atopic dermatitis signs in clinical practice.
Le texte complet de cet article est disponible en PDF.Abbreviations used : BSA, EASI, SGA
Plan
Funding sources: None. |
|
Conflicts of interest: None disclosed. |
|
Presented as a Selected ePoster Discussion at the Society for Investigative Dermatology Annual Meeting, May 8 to May 11, 2019. |
|
IRB approval status: Approved by the institutional review board at Oregon Health & Science University (IRB 19264). |
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?