Clinical and dermoscopic characteristics of congenital and noncongenital nevus-associated melanomas - 08/09/20
Abstract |
Background |
No specific features of nevus-associated melanoma (NAM) are currently defined.
Objective |
To identify clinical/dermoscopic features of NAM.
Methods |
Retrospective evaluation of histopathologically diagnosed NAM.
Results |
Eighty of 165 NAMs had a clinically recognizable nevus component, often raised or nodular, most frequently characterized by different morphologic clones and/or colors. In 111 of 165 NAMs, dermoscopy showed a nevus component, prevalently characterized by regular dots/clods and structureless brown areas. Clinically, the melanoma component was eccentric/peripheral in 45 of 80 cases and central in 35 of 80; dermoscopically, the figures were 59 of 111 and 52 of 111, respectively. Melanomas associated with congenital nevi (C-NAMs) occur at a younger age and have a thicker Breslow depth than melanomas associated with acquired nevi (NC-NAMs). Dermoscopically, regular dots/globules characterize C-NAMs, and hypopigmented structureless areas characterize NC-NAMs.
Limitations |
Retrospective analysis.
Conclusion |
C-NAMs are more often central to a congenital nevus, with a clod/globular or structureless brown pattern, typical of young patients. NC-NAMs are frequently hypopigmented nodules/plaques, eccentric/peripheral, with hypopigmented structureless areas, typical of older patients.
Le texte complet de cet article est disponible en PDF.Key words : dermoscopy, melanoma, nevogenesis, nevus, nevus-associated melanoma, skin cancer
Abbreviations used : C-NAM, NAM, NC-NAM
Plan
| Drs. Zalaudek and Conforti are cofirst authors. |
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| Funding sources: None. |
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| Conflicts of interest: None disclosed. |
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| IRB approval status: The study was approved by the IRB of Graz. |
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| Reprints not available from the authors. |
Vol 83 - N° 4
P. 1080-1087 - octobre 2020 Retour au numéro
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