Diagnostic benefit of high b-value computed diffusion-weighted imaging in acute brainstem infarction - 07/10/20
Cet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Graphical abstract |
Highlights |
• | Diffusion-weighted imaging as a cornerstone in diagnostic of ischemic stroke. |
• | Computed diffusion-weighted imaging requires no additional image acquisition time. |
• | High b-value provides improved visibility for ischemic brainstem lesions. |
• | High b-value images lead to more imaging artifacts. |
• | The b-2000 image is recommended to use in clinical routine. |
Abstract |
Background and purpose |
Diffusion-weighted imaging (DWI) is a cornerstone in diagnostic of ischemic stroke. The aim of this study was to investigate the usefulness of high-b-value computed DWI (c-DWI) in comparison to standard DWI in patients with acute brainstem infarction.
Materials and methods |
56 patients with acute brainstem infarction were retrospectively analysed by two readers. DWI was obtained with the b-values 0, 500 and 1000 s/mm² on either a 1.5 or 3 T magnetic resonance imaging (MRI) scanner. c-DWI was calculated with a monoexponential model with high b-values 2000, 3000, 4000 and 5000 s/mm². All c-DWI series with high-b-values were compared to the standard DWI sequence at b-value of 1000 s/mm² in terms of image artifacts, lesion extent and contrast.
Results |
There was no statistically significant difference between 1.5 and 3 T MRI regarding the measured ischemic lesion size. There were no statistically significant differences between the ischemic lesion sizes on DWI at b-values of 1000 s/mm² and on c-DWI at higher b-values. Overall, the contrast between the lesion and the surrounding normal areas improved with increasing b-value on the isotropic DWIs: maximum at b = 5000, followed by that at b 2000 and b 1000 s/mm², in order. The best relation between artifacts and lesion contrast was identified for b 2000 s/mm².
Conclusion |
High b-value DWI derived from c-DWI has a higher visibility for ischemic brainstem lesions compared to standard DWI without additional time cost. The b-2000 image is recommended to use in clinical routine, higher b-value images lead to more imaging artifacts, which might result in misdiagnosis.
Le texte complet de cet article est disponible en PDF.Keywords : Computed diffusion-weighted imaging, High-b-value, Brainstem, Infarction
Plan
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?