Surgical removal of deep infiltrating endometriosis lesions is associated with improved spontaneous fertility outcome in infertile women.
Surgeon’s learning curve does not impact postoperative fertility outcomes.
Surgery for deep endometriosis leads to improved spontaneous fertility in infertile women.
To determine whether the surgical learning curve impact the spontaneous pregnancy rate in infertile patients undergoing removal of deep infiltrating endometriosis
Material and Methods
Single center retrospective study including the first 50 consecutive infertile women suffering from deep infiltrating endometriosis and referred to a single surgeon. All patients underwent laparoscopic removal of deep endometriosis lesions. The study population was stratified in two subgroups, namely the early group (including the first 25 cases) and the late group (comprising the 25 subsequent cases). Pregnancy and live birth rates, surgical morbidity and clinical recurrence rate were compared between study groups.
Overall, spontaneous pregnancy rate (40 % in the early group versus 56 % in the late group, p = 0.25), live birth rate (40 % versus 44 %, p = 0.77) and clinical recurrence rate (16 % versus 4%, p = 0.16) did not significantly differ between the study groups. Logistic regression analysis revealed that ASRM stage, EFI score, and body mass index were the only significant prognostic factors of postoperative spontaneous fertility.
Surgical resection of deep infiltrating endometriosis in infertile women is associated with high spontaneous pregnancy and live birth rates. The surgeon’s learning curve does not impact postoperative fertility outcomes.Le texte complet de cet article est disponible en PDF.
Abbreviations : AMH, ART, ASRM, CNIL, DIE, EFI, FSH, LBR, LH, MRI, SPR
Keywords : Deep infiltrating endometriosis, Surgery, Learning curve, Fertility, Spontaneous pregnancy