Roles of Annexin A protein family in autophagy regulation and therapy - 27/10/20
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Graphical abstract |
Highlights |
• | Annexin A family protein is associated with autophagy. |
• | Annexin A can regulate the formation of vesicular lipid membranes. |
• | Annexin A can promote cell exocytosis. |
• | Annexin A protein is a novel target for disease therapy. |
Abstract |
Annexin A is a kind of calcium-dependent phospholipid-binding proteins, which contributes to the formation of the cell membranes and cytoskeleton and played a part as a membrane skeleton to stabilize lipid bilayer. Autophagy is one of the most important programmed cell death mechanisms. And recently some reports suggest that annexin A family protein is associated with autophagy for annexin A can regulate the formation of vesicular lipid membranes and promote cell exocytosis. In this review, we summarized the roles of annexin A protein family in autophagy regulation and targeted medical treatment for better diagnoses and therapies.
Le texte complet de cet article est disponible en PDF.Keywords : Autophagy, Annexin A, Protein, Vesicular lipid membranes, Calcium-dependent phospholipid-binding proteins, Targeted medical therapy
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Vol 130
Article 110591- octobre 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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