Severe COVID-19 presents as multiple organ dysfunction syndrome (SARS-CoV-2 MODS).
Less is more in ventilating critically ill patients with severe COVID-19 pneumonia.
European Medicines Agency released approval for administration of steroids.
Main therapeutic targets: anti-inflammatory; anticoagulation; protective ventilation.
The 2020 International Web Scientific Event in COVID-19 pandemic in critically ill patients aimed at updating the information and knowledge on the COVID-19 pandemic in the intensive care unit. Experts reviewed the latest literature relating to the COVID-19 pandemic in critically ill patients, such as epidemiology, pathophysiology, phenotypes of infection, COVID-19 as a systematic infection, molecular diagnosis, mechanical ventilation, thromboprophylaxis, COVID-19 associated co-infections, immunotherapy, plasma treatment, catheter-related bloodstream infections, artificial intelligence for COVID-19, and vaccination. Antiviral therapy and co-infections are out of the scope of this review. In this review, each of these issues is discussed with key messages regarding management and further research being presented after a brief review of available evidence.Le texte complet de cet article est disponible en PDF.
Keywords : COVID-19, SARS-CoV-2, Pneumonia, Acute respiratory failure, ARDS, Intensive care