Histological analysis of socket preservation using DBBM. A systematic review and meta-analysis - 11/12/20
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Abstract |
Purpose |
Deproteinized bovine bone mineral (DBBM) is a type of bone substitute material widely used in tooth extraction sites. However, there is a lack of evidence supporting the benefit of DBBM used for postextraction socket preservation with regard to new bone formation. This meta-analysis and systematic review was conducted to explore whether site preservation (SP) using DBBM could provide benefits with regard to new bone formation compared with natural healing.
Materials and methods |
Studies reporting histological results for postextraction SP with DBBM and natural healing from 2000 to 2019 were identified in three databases, and a meta-analysis was conducted.
Results |
Five studies were included. The DBBM group had a significantly lower new bone percentage than the natural healing group, with a MD of −24.75 [95%CI: −39.77, −9.73] (P=0.001). The percentage of connective tissue in the extraction site was not significantly different between the two groups, with a MD of 0.60 [95%CI: −4.85, 6.05] (P=0.83).
Conclusions |
SP using DBBM provided no additional benefit with regard to postextraction new bone formation in comparison with natural healing. Due to the lack of high-quality research, further large-sample studies and standard studies are needed to confirm these conclusions.
Le texte complet de cet article est disponible en PDF.Keywords : Socket preservation, Xenograft, DBBM, Meta-analysis, Bio-Oss, Bio-Oss Collagen
Plan
Vol 121 - N° 6
P. 729-735 - décembre 2020 Retour au numéro
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