Cancer evolution: A means by which tumors evade treatment - 19/12/20
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Highlights |
• | Tumor heterogeneity is an important intrinsic cause. |
• | Several factors influencing cancer evolution are demonstrated. |
• | Six types of cancer evolution models are emphasized. |
• | Several treatment options are listed based on the research results of cancer evolution. |
Abstract |
Although various methods have been tried to study and treat cancer, the cancer remains a major challenge for human medicine today. One important reason for this is the presence of cancer evolution. Cancer evolution is a process in which tumor cells adapt to the external environment, which can suppress the human immune system's ability to recognize and attack tumors, and also reduce the reproducibility of cancer research. Among them, heterogeneity of the tumor provides intrinsic motivation for this process. Recently, with the development of related technologies such as liquid biopsy, more and more knowledge about cancer evolution has been gained and interest in this topic has also increased. Therefore, starting from the causes of tumorigenesis, this paper introduces several tumorigenesis processes and pathways, as well as treatment options for different targets.
Le texte complet de cet article est disponible en PDF.Keywords : Key words, Cancer evolution, Tumor heterogeneity, Drug resistance, Evolution model, Oncotherapy
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Vol 133
Article 111016- janvier 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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