Coronary disease represents a major cause of morbidity and mortality worldwide.

To determine biological factors predicting in hospital death following primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI).

We reviewed data from retrospective registry including 352 patients admitted in cardiology B department from January 2000 to March 2017 for STEMI. All patients were managed by primary PCI.

In hospital mortality rate was 11.9% in population study. It was higher in women (23.2% vs. 9.8%; P=0.005). Its biological predicting factors in univariate analysis were severe anemia with hemoglobin level below 8g/dl (P<0.001), renal failure (P<0.001), hyperglycemia (blood glucose level greater than 11mmol/l) (P<0.001), leukocytosis (white blood cells count over 14.000/mm³) (P=0.005) and platelet count over 250.000/mm³ (P=0.037). In multivariate analysis, only renal failure and anemia were independent predicting factors of in hospital mortality (P<0.001).

Recognizing and understanding the biological risk factors of mortality after STEMI provide clinician important information to determine prognosis.