The prevalence of heart failure (HF) continues to rise due to aging population, acute renal injury (ARI) is a common complication in patients admitted with decompensated HF, the interaction between HF and ARI is complex, bidirectional, and interdependent;
The main goal of this investigation was to determine the incidence of new-onset ARI in patients admitted with HF, and to evaluate the impact of developing AKI in-hospital mortality.
This is a retrospectif study, including all patients admitted for HF in CHU Casablanca cardiology department from January 2016 to September 2019, patients were divided into two groups: HF with and without Acute renal injury These groups were further divided into the subgroups HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF).
The main age was 60,45±15,7, Sex ratio: 1,5 (60,9% male, 39,1% female) the incidence of acute renal injury at hospital presentation was 46,4%, there was a significant relation between ARI and sex, with a higher risk for women [OR=1,5; 95% [CI], 1,02–2,37].; P=0,028), in-hospital mortality was higher in the HF with ARI group [OR: 1,13 (1,05–1,2), P≤0.021] and higher among patients with HFrEF (OR 1,39) length of stay for the HF with ARI group were significantly higher as well (OR: 1,2, P=0,013)
ARI is associated with worse in-hospital mortality in hospitalizations for heart failure. Therefore, this may lead to an increase in the length of stay and in the overall cost of care. Patients hospitalized for heart failure who develop new-onset AKI may require a change in the standard of care to reduce adverse events.
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Publié par Elsevier Masson SAS.