Cardiac resynchronisation therapy (CRT) is an effective treatment for heart failure (HF) in ischemic and non-ischemic cardiomyopathy (NIDCM) with widened QRS interval. However, the results of CRT in patients with valvular heart disease (VHD) are poorly known, as they are not isolated within the group of NIDCM.

Present the profile of our patients with VHD who received CRT and to evaluate the initial results.

We included patients diagnostic with post-surgical valvular cardiomyopathy. All the patients had undergone valve replacement surgery with left ventricular dysfunction and heart failure with no other obvious etiology. They all had widened QRS interval and left ventricular ejection fraction (LVEF) ≤35% in optimal medical treatment of chronic HF for at least 12 weeks.

From January 2015 to December 2016, 30 consecutive patients with VHD, from a total of 100 patients (30%), received CRT (23 men and 7 women middle-aged of 59.9–9.6 years). Twenty-one patients were in NYHA class III and the others in class IV, a mean LVEF 29%±4 and a mean QRS duration 159±4msec. Twenty over thirty patients were in chronic atrial fibrillation; half of them required an AV node radiofrequency ablation. Eighteen patients had received CRTP and 12 of them CRTD. After 6 months of follow-up, 18/30 patients were in class II NYHA (P<.001) and 22/30 patients significantly improve their six minutes walk in an average of 36% (P<.001). The left ventricular end diastolic volume (LVEDV) was decreased at least about 15% in 16/30 patients (53.3%; P<.001) and the LVEF was improved about at least 10% in 24/30 patients (80%; P<.001). At six months, 2 patients were dead following an acute heart failure.

Implantation of CRT devices can be performed safely with a high procedure success, leading to an improved of clinical status and left ventricular function in these patients with post-surgical valvular cardiomyopathy.