Spontaneous osteonecrosis of the jaw in a ?-Thalassemia intermedia patient - 07/04/21
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Highlights |
• | Patients with thalassemia have a variety of dental and oral manifestations. |
• | Spontaneous osteonecrosis of the alveolar bone in thalassemia patients can occur as reported in this case. |
• | Consultation with haematologist may be necessary for surgical management depending on the severity of the thalassemia. |
• | The exact pathogenesis for the osteonecrosis is unclear but the prognosis of the osteonecrosis appears to be good. |
Abstract |
The resultant anemia in hemoglobinopathies like thalassemia can lead to expansion of the bone marrow cavities due to compensatory hyperplasia. This article reports a case of spontaneous osteonecrosis of the left maxillary alveolus in a patient with β-Thalassemia intermedia. The area affected presented as areas of osteosclerosis on the radiographic examination and sequestrectomy of the left maxillary alveolus was performed after consultation with his hematologist. The exact pathogenesis for the osteonecrosis is unclear. One possible postulation for the cause of osteonecrosis in our case could be that the alveolar bone suffered ischemic infarction secondary to occlusion of the microvasculature within the expanded cancellous bone.
Le texte complet de cet article est disponible en PDF.Keywords : Oral pathology, Osteonecrosis, Hemoglobinopathies, Thalassemia, Marrow hyperplasia
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