Adnexal masses in patients with colorectal cancer - 15/04/21
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Abstract |
Objective |
To evaluate the clinicopathological features and outcomes of patients undergone surgery for benign and metastatic adnexal masses during the surveillance of colorectal cancer (CRC).
Methods |
A single institute retrospective study involving 90 patients diagnosed with CRC that undergone surgery at Hacettepe University Hospital between 2000−2018. Clinicopathological and survival data was obtained from hospital records.
Results |
Elevated blood levels of CEA (HR, 1.23; 95 % CI: 1.03–1.24; p = 0.01), adnexal masses larger than 5 cm (HR, 3.296; 95 % CI: 1.527–7.076; p = 0.002), bilaterality of adnexal mass (HR, 2.200; 95 % CI: 2.464–11.969; p = 0.001) and high PCI score (HR, 0.150; 95 % CI: 0.044−0.479; p = 0.01) were found to be significantly associated with ovarian metastasis. There was a significant difference in overall survival (OS), with respect to complete and incomplete resection in adnexal surgery of ovarian metastasis (46.6 vs. 29.6 months; p = 0.004). The median survival time was 32.8 months for patients with ≤ 24 months interval time to adnexal metastasis surgery, and 48.5 months for patients with >24 months interval time to adnexal metastasis surgery (p = 0.001).
Conclusion |
This study showed that numerous clinicopathological variables such as bilaterality and size of adnexal mass, serum blood levels of CEA and PCI score may have a significant impact on the prediction and management of ovarian masses diagnosed during CRC surveillance. Complete resection and interval time to adnexal surgery is significantly associated with OS.
Le texte complet de cet article est disponible en PDF.Keywords : Colorectal cancer, Ovarian metastasis, Adnexal mass
Plan
Vol 50 - N° 5
Article 101898- mai 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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