Invasive pulmonary aspergillosis associated with Covid-19 has been reported.
Incidence of aspergillosis associated with Covid-19 is still to be determined.
Means of diagnosis for pulmonary aspergillosis in Covid-19 need to be evaluated.
Multiple definitions for probable invasive pulmonary aspergillosis exist.
A consensus definition for Covid-19-associated pulmonary aspergillosis is needed.
Invasive pulmonary aspergillosis is a well-known complication of acute respiratory distress syndrome, the most serious manifestation of COVID-19. Four recent studies have reported its incidence among ICU COVID-19 patients. However, they do not share the same case definition, and have provided conflicting results. In this paper we have aimed at reported the incidence of invasive pulmonary aspergillosis for COVID-19 patients in our ICU, and at comparing the different definitions in order to assess their respective relevance.
Retrospective cohort study of critically ill patients with severe COVID-19 requiring ICU management between 1st March and 30th April 2020.
Our results showed significantly lower incidence of invasive pulmonary aspergillosis (1.8%;1/53), compared to three out of four previous studies, and wide variation in the numbers of cases with regard to the different definitions.
Large-scale studies are needed for a better definition and a more accurate estimation of invasive pulmonary aspergillosis coinfection during COVID-19.Le texte complet de cet article est disponible en PDF.
Keywords : COVID-19, Aspergillosis, Coronavirus Infections/pathology, Pulmonary Aspergillosis/diagnosis