Contrast-enhanced T1-weighted Dixon water- and fat-only images to assess osteitis and erosions according to RAMRIS in hands of patients with early rheumatoid arthritis - 26/06/21
Highlights |
• | Contrast-enhanced T1-weighted Dixon water-only images allow reproducible assessment of osteitis in hands of patients with early rheumatoid arthritis and could replace the recommended fat-saturated T2-weighted sequence. |
• | Contrast-enhanced T1-weighted Dixon fat-only images allow reproducible assessment of erosions in hands of patients with early rheumatoid arthritis and could replace the recommended non-enhanced T1-weighted sequences. |
Abstract |
Purpose |
To assess the agreement between readers using contrast-enhanced T1-weighted Dixon water- and fat-only images and OMERACT-recommended sequences for the scoring of osteitis and erosions according to the rheumatoid arthritis (RA) MRI scoring system (RAMRIS) in hands of patients with early RA.
Materials and methods |
Both hands of 24 patients (16 women, 8 men; mean age, 45.7±14.5 [SD] years; age range: 25–70 years) with early RA were prospectively imaged with fat-saturated T2-weighted sequences, non-Dixon T1-weighted imaging prior to contrast material injection and T1-weighted Dixon imaging after contrast material injection at 1.5T. There were Two radiologists separately quantified osteitis and erosions according to RAMRIS using contrast-enhanced T1-weighted Dixon water-only and fat-saturated T2-weighted images for osteitis and contrast-enhanced T1-weighted Dixon fat-only and T1-weighted images prior to contrast material injection for erosions. Intraclass correlation coefficients (ICC) were calculated to assess inter-technique, intra-observer and inter-observer agreement.
Results |
Mean ICC for the agreement between Dixon and non-Dixon images ranged from 0.68 (95%CI: 0.20–0.90) to 0.99 (95%CI: 0.95–1.00) for the scoring of osteitis and from 0.77 (95%CI: 0.38–0.93) to 0.99 (95%CI: 0.95–1.00) for the scoring of erosions. Mean ICC for the agreement between first and second readings ranged from 0.94 (95%CI: 0.81–0.98) to 0.97 (95%CI: 0.91–0.99) for the scoring of osteitis using Dixon and 0.91 (95%CI: 0.72–0.97) to 0.98 (95%CI: 0.92–0.99) using non-Dixon images and from 0.80 (95%CI: 0.45–0.94) to 0.97 (95%CI: 0.91–0.99) for the scoring of erosions using Dixon and 0.72 (95%CI: 0.29–0.91) to 0.98 (95%CI: 0.92–0.99) using non-Dixon images.
Conclusion |
Contrast-enhanced T1-weighted Dixon water- and fat-only images can serve as an alternative to fat-saturated T2-weighted and T1-weighted MRI sequences for the assessment of osteitis and erosions according to the RAMRIS scoring system in hands of patients with early RA.
Le texte complet de cet article est disponible en PDF.Keywords : Arthritis, Rheumatoid, Magnetic resonance imaging, Osteitis, Arthropathy, Erosive, Hand bones
Abbreviations : 2D, 3D, GRE, ICC, MRI, OMERACT, RA, RAMRIS, SE, SD, STIR
Plan
Vol 102 - N° 7-8
P. 439-445 - juillet 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.