A case of Francisella tularensis meningitis in a 64-year-old man treated with quinolones - 21/07/21
, S. Melboucy b, H. Bentayeb a, C. Dayen a, R. Suguenot a, E. Lecuyer a, Y. Douadi aCet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Highlights |
• | There are no guidelines for tularemic meningitis, which is a rare but serious condition. |
• | The historical treatment is based on old and toxic molecules. Quinolones could be a more up-to-date alternative. |
• | Francisella tularensis meningitis should be suspected based on clear cerebrospinal fluid, mostly with lymphocytes. |
Abstract |
We report a French case of tularemic meningitis – the second to be thoroughly described – and discuss the existing literature.
The patient is a 64-year-old man with no medical history, who developed fever, cutaneous symptoms, and swollen lymph nodes within a week after a hunt. He was then diagnosed with meningitis caused by Francisella tularensis subsp. holarctica.
Healing was quickly achieved ad integrum within 3 weeks with a course of ciprofloxacin.
We discuss the existing literature about this specific issue, and try to shine a light on the superior efficacy and lesser toxicity of quinolones compared to the historical treatment.
Le texte complet de cet article est disponible en PDF.Keywords : Meningitis, Treatment, Tularemia
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