Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon - 09/10/21
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Abstract |
In the last few decades, utilization of medicinal plants by the pharmaceutical industry has led to the identification of many new bioactive compounds. The genus Pterodon, native of the Brazilian Flora, is known for the therapeutic properties attributed to its species, which are widely used in popular medicine for their anti-inflammatory, anti-rheumatic, tonic, and depurative properties. The intrinsic low water solubility of the plant derivatives from the genus, including diterpenes with vouacapane skeletons that are partially associated with the pharmacological activities, impairs the bioavailability of these bioactive compounds. Recent studies have aimed to encapsulate Pterodon products to improve their water solubility, achieve stability, increase their efficacy, and allow clinical applications. The purpose of this paper is to review recent research on the use of nanotechnology for the development of new products from plant derivatives of the Pterodon genus in different types of micro- and nanocarriers. Therapeutic properties of their different products are also presented. Finally, an update about the current and future applications of encapsulated formulations is provided.
Le texte complet de cet article est disponible en PDF.Graphical Abstract |
Highlights |
• | Micro and nanostructured systems could act as delivery platforms for natural extracts. |
• | Micro and nano-encapsulation of plant bioactive derivatives have been shown enhanced biological activity. |
• | Encapsulated extracts, oils, and phytochemicals of the genus Pterodon has shown promising biological activities. |
Keywords : Pterodon, Encapsulation, Polymeric nanoparticle, Lipidic nanoparticle, Terpenes, Natural products
Plan
Vol 143
Article 112137- novembre 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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