Lamiophlomis herba: A comprehensive overview of its chemical constituents, pharmacology, clinical applications, and quality control - 13/11/21
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Abstract |
Lamiophlomis rotata (Benth.) Kudo (LR) is an extensively used Chinese herbal medicine. It contains a variety of chemical constituents with significant biological activities that were first recorded in the classical masterpiece of Tibetan Medicine, Somaratsa. In this review, we summarize the information regarding the traditional uses, chemical constituents, pharmacological effects, clinical applications, quality control, toxicology, and pharmacokinetics of LR. At least 223 chemical constituents have been isolated from LR, including phenylethanoid glycosides, flavonoids, iridoids, volatile oils, et al. Their various physiological activities have been demonstrated as analgesic, hemostatic, anti-inflammatory, anti-tumor, marrow-supplementing, anti-bacterial, and immunity-strengthening. The clinical applications of LR and quality control are also discussed, as well as some existing problems. This article aims to provide more comprehensive information on the chemical composition, pharmacological activity, and clinical application of LR, so as to provide a theoretical basis for the further reasonable development of LR in clinical practice and of new drugs.
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Highlights |
• | 223 chemical components have been isolated from the Lamiophlomis rotata (Benth.) Kudo (LR). |
• | LR has various functions such as analgesic, hemostatic and anti-inflammatory. |
• | The clinical applications and quality control of LR were systematically summarized for the first time. |
• | Some feasible suggestions for future development of LR were provided. |
Keywords : Lamiophlomis rotata (Benth.) Kudo (LR), Traditional uses, Chemical constituents, Pharmacology, Quality control, Clinical applications
Plan
Vol 144
Article 112299- décembre 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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