Were magnetic materials useful in cancer therapy? - 13/11/21

Doi : 10.1016/j.biopha.2021.112321

Roghayyeh Baghban ^a,^b, Mehrdad Afarid ^a, Jafar Soleymani ^c,^⁎ , Mahdi Rahimi ^d,^⁎
^a Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
^b Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
^c Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
^d Lodz University of Technology, Institute of Polymer and Dye Technology, Stefanowskiego 16, 90–537 Lodz, Poland

^⁎Corresponding author.^⁎⁎Correspondence to: Faculty of Chemistry, Institute of Polymer and Dye Technology, Lodz University of Technology, Lodz, Poland.Faculty of Chemistry, Institute of Polymer and Dye Technology, Lodz University of TechnologyLodzPoland

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Abstract

Cancer is one of the major challenges fronting the biomedical basic researches in our time. The study and development of effective therapeutic strategies for cancer therapy are vital. Among the many probable core constituents of nanoparticles, magnetite-based nanoparticles have been widely studied for cancer therapy owing to their inherent magnetic features, multifunctional design, biodegradable and biocompatible properties. Magnetic nanoparticles have been also designed for utilizing as contrast enhancer agents for magnetic resonance imaging, drug delivery systems, and most recently as a therapeutic element in inducing cellular death in tumor ablation therapies. This review aimed to provide an overview of the various applications of magnetic nanoparticles and recent achievements in developing these advanced materials for cancer therapy.

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Keywords : Cancer, Magnetic nanoparticles, Therapeutic strategies, Advanced materials