Implication of the Nature and Texturation of Silicone Surfaces on the Grafting of PolyNaSS, a Bioactive Polymer - 22/12/21
Cet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Graphical abstract |
Highlights |
• | Study of the implication of the topography on the grafting of the bioactive polymer under UV irradiations. |
• | Study of the type of silicone on the grafting of the bioactive polymer under UV irradiations. |
• | The roughness and the nature of silicone have an influence on the grafting quality. |
Abstract |
Objective |
The publication aims to characterize the particularities of breast implant outer shells' structure and roughness. Then, it seeks to study the implication of the topography and the type of silicone on the grafting of the bioactive polymer under UV irradiations.
Material & methods |
PolyNaSS was grafted on silicone surfaces via a radical polymerization under 365 nm UV irradiation. Surface characterizations were accessed using scanning electron microscopy (topography), water contact angle measurements, infrared spectroscopy, and colorimetric assays (grafting density). A viability test was carried with L929 fibroblasts using MTT reagent.
Results |
Polydiphenylsiloxane (PDPS) has improved the grafting protocol thanks to the reactivity of phenyl groups under UV irradiation compared to polydimethylsiloxane (PDMS) but exhibits low viability rates in contact with fibroblasts.
Conclusion |
The roughness of silicone surfaces or the nature of silicone influence the grafting quality. PDPS could not be considered as an alternative to PDMS from a biological point of view.
Le texte complet de cet article est disponible en PDF.Keywords : Silicone, Bioactive polymer, Grafting, Biocompatibility, Roughness
Plan
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?