Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus - 12/01/22
pages | 5 |
Iconographies | 0 |
Vidéos | 0 |
Autres | 0 |
Highlights |
• | The initial assessment of HCV infection must assess liver disease severity. |
• | Regular HCV viral load testing is recommended in patients who engage in risky reinfection behaviours. |
• | Hepatocellular carcinoma screening must continue in patients with advanced liver fibrosis prior to treatment initiation. |
• | Liver biopsy is only recommended when the results could influence subsequent patient monitoring. |
Abstract |
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosis and improvements in therapy with pangenotypic direct antivirals and prevention. These AFEF guidelines on the non-invasive diagnosis and follow up of chronic infection with HCV describe the optimal management of HCV positive patients with non-invasive methods in screening, in assessing viral disease and liver fibrosis and the follow-up of these patients according to the value of FibroScan®, Fibrotest® or Fibrometer®. Hepatocellular carcinoma screening must continue in patients with liver stiffness by FibroScan® ≥10 kPa or Fibrotest® >0.58 or Fibrometer® >0.78 prior to treatment initiation. After reaching sustained virologic response, patients with a measurement of liver stiffness by FibroScan®<10 kPa or Fibrotest®≤0.58 or Fibrometer®≤0.78 before treatment initiation and without liver comorbidity (alcohol consumption, metabolic syndrome, HBV co-infection etc.) no longer require specific monitoring. The role of liver biopsy is discussed in some rare situations.
Le texte complet de cet article est disponible en PDF.Plan
Vol 46 - N° 1
Article 101771- janvier 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?