COVID-19 reinfection after pregnancy - 27/02/22
, A. Vallée a, ⁎ , D. Zucman b , M. Carbonnel c , J. Laperrelle c , O. Brugière d , A. Martin a , J.-M. Ayoubi c , E. Farfour b
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Highlights |
• | Report of a case of COVID-19 reinfection with a first mild infection during late pregnancy and a more aggressive second infection 5 months later. |
• | Reinfection due to a variant viral strain could be a possibility as numerous new and more aggressive variants are described. |
• | Apparent paradox between declining antibody levels and low incidence of reinfection, implying other immune mechanisms at work, including T lymphocytes. |
• | The role of HLA-G immuno-inhibitor may be questioned and may be a possible treatment. |
Abstract |
Background |
There have been reports of COVID-19 reinfections, but the immunological characterization of these cases is partial. We report a case of reinfection with SARS-CoV-2, where the first infection occurred in the course of late pregnancy.
Case presentation |
On May 27, 2020, a 37-year-old woman gave birth at full term, 3 hours after full dilatation. She developed fever (38.3°C) after delivery. Mild biological anomalies compatible with COVID-19 were observed: lymphopenia, thrombocytopenia, elevated D-Dimers, CRP, and LDH. At 6-month follow-up, she reported having contracted COVID-19 with high fever, rhinorrhea, hand frostbites, cough, headache, dysgeusia and anosmia.
Conclusions |
We report a case of COVID-19 reinfection with a first mild infection during late pregnancy and a more aggressive second infection 5 months later.
Le texte complet de cet article est disponible en PDF.Keywords : COVID-19, Pregnancy, Reinfection
Plan
Vol 52 - N° 2
P. 101-103 - mars 2022 Retour au numéro
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