Association between the duration of antibiotic prophylaxis and surgical site infection after orthognathic surgery in Japan - 29/06/22

Doi : 10.1016/j.jormas.2022.06.009

Shigeo Ishikawa ^a,^⁎ , Keita Morikane ^b, Tsuneo Konta ^c, Shohei Ueda ^a, Kazuyuki Yusa ^a, Naoki Okuyama ^a, Satoshi Kasuya ^a, Shunsuke Kunii ^a, Nagiko Suzuki ^a, Moe Eguch ^a, Kaori Maehara ^a, Mitsuyoshi Iino ^a
^a Department of Dentistry, Oral and Maxillofacial Plastic and Reconstructive Surgery, Faculty of Medicine, Yamagata University, Yamagata, Japan
^b Division of Clinical Laboratory and Infection Control, Yamagata University Hospital, Yamagata, Japan
^c Department of Public Health and Hygiene, Yamagata University Graduate School of Medicine, 2-2-2 Iida-nishi, Yamagata 9909585, Japan

^⁎Corresponding author.

Sous presse. Épreuves corrigées par l'auteur. Disponible en ligne depuis le Wednesday 29 June 2022
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Abstract

Purpose

This study aimed to evaluate the risk factors for surgical site infection (SSI) after orthognathic surgery, focusing on the duration of prophylactic antibiotic administration in Japan.

Study Design

The study included 181 patients who underwent orthognathic surgery at the Department of Oral and Maxillofacial Surgery of Yamagata University Hospital between 2012 and 2021. The clinical parameters of SSI were retrospectively investigated using patient charts. Logistic regression analysis was used to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) for risk factors for SSI after orthognathic surgery.

Results

Nineteen patients (10.5%) were complicated with SSI. Male sex (OR, 3.638; 95% CI, 1.316–10.058) and an antibiotic prophylaxis duration ≤3 days (OR, 12.718; 95% CI, 1.639–98.673) were independent risk factors for SSI after orthognathic surgery.