Age- and sex-specific effects of obesity, metabolic syndrome and its components on back pain: The English Longitudinal Study of Ageing - 21/09/22
, Lingxiao Chen c, Manuela L Ferreira c, Nigel K Arden d, e, Maja R Radojčić b, d, 1, Stefan Kluzek d, f, 1Highlights |
• | Body mass index is associated with back pain in middle-aged and older women and men. |
• | Metabolic syndrome is associated with back pain only in women. |
• | High waist circumference drives the effect of metabolic syndrome in women. |
• | Metabolic syndrome contributes to the severity of back pain. |
Abstract |
Objectives |
We aimed to investigate age- and sex-specific effects of obesity, metabolic syndrome (MetS) and its components on back pain in middle-aged and older English individuals.
Methods |
We used data from the English Longitudinal Study of Ageing, wave 2 (2004–2005). Body mass index (BMI) expressed the obesity, while MetS was defined according to revised Adult Treatment Panel (ATP) III criteria. We assessed associations between obesity, MetS and its components with presence and severity of back pain and provided estimates per strata, middle-aged (50–64years) and older (65–79years), women and men.
Results |
The study sample included 3328 participants, 1021 and 835 middle-aged women and men and 773 and 699 older women and men, respectively. We found that BMI (OR=1.07, 95% CI 1.05–1.09), MetS (OR=1.47, 95% CI 1.22–1.77), high waist circumference (WC), high triglycerides (TG), and high fasting blood glucose were associated with the presence of back pain. Effects of BMI were consistent across the strata. However, MetS was associated with back pain only in women, middle-aged (OR=1.59, 95% CI 1.14–2.21) and older (OR=1.43, 95% CI 1.01–2.05). The MetS component driving this association was high WC, supported by high TG in older women. Higher BMI, presence of MetS, high blood pressure and TG were associated with back pain severity.
Conclusions |
We found that obesity was associated with the presence and severity of back pain, irrespective of age and sex. However, we found women-specific effects of MetS driven by high WC, indicating that metabolic dysregulation contributes to back pain pathophysiology in women.
Le texte complet de cet article est disponible en PDF.Keywords : Back pain, Body mass index, Metabolic syndrome, Waist circumference, Sex differences
Plan
Vol 89 - N° 5
Article 105366- octobre 2022 Retour au numéro
Article précédent
- Changes in bone mineral density after allogenic stem cell transplantation
- Diane Leguy, Leonardo Magro, Adeline Pierache, Valérie Coiteux, Ibrahim Yakoub Agha, Bernard Cortet, Isabelle Legroux-Gerot
- Phenotype and cytokine profile in a TRAPS Syndrome family with TNFRSF1A p.(Thr79Met): Association with sacro-iliitis
- Glory Dingulu, Adriana Delwail, Laurence Cuisset, Jean-Claude Lecron, Elisabeth Gervais
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?