Life-threatening hemophagocytic syndrome triggered by disseminated toxoplasmosis in a young patient with previously unknown AIDS - 02/10/22
Syndrome d'activation macrophagique sévère associé à une toxoplasmose disséminée, inaugurale d'une infection VIH au stade SIDA chez un jeune patient en réanimation
Abstract |
Hemophagocytic syndrome is a rare life-threatening disorder that can be triggered by various conditions such as HIV infection and opportunistic agents. We report a case of disseminated toxoplasmosis complicated with severe hemophagocytic syndrome and revealing an unknown acquired immunodeficiency syndrome. The patient presented with multiple organ failure in intensive care unit. Once diagnosed, he benefitted from etoposide infusion, administration of specific anti-toxoplasmosis treatments and secondary antiretroviral therapy. He was alive at intensive care unit discharge and returned home with little sequalae. This case illustrates both the importance of rapid investigations of hemophagocytic syndrome etiologies in HIV positive patients and the necessity to prompt etoposide and specific treatments in order to improve potentially dramatic outcomes.
Le texte complet de cet article est disponible en PDF.Keywords : Lymphohistiocytosis, Hemophagocytic, Toxoplasmosis, Acquired Immunodeficiency Syndrome, Immunocompromised Host, Critical care
Abbreviation : HS, AIDS, HIV, HAART, EBV, ICU, CT, PCR, CMV, AKI, SAPSII, CSF, RRT, PCP, ARV
Plan
Vol 43 - N° 10
P. 622-625 - octobre 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?