Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note - 20/01/23
, R. Aboukaïs a, b, P. Bourgeois a, N. Reyns a, b, J.-P. Lejeune a, bHighlights |
• | Gliomas are diffuse intra-axial lesions, which can be accessed by multiple surgical corridors depending on their location and surgeon's preference. |
• | The use of 5-Aminolevulinic Acid (5-ALA) facilitates the extent of resection of high grade gliomas. |
• | 5AlA-guided resection of fronto-basal HGG via minimal invasive supraorbital transciliary approach is a safe and effective procedure in selected cases. |
Abstract |
Background |
Gliomas are diffuse intra-axial lesions, which can be accessed by multiple surgical corridors for a same location depending on the surgeon's preference. 5-Aminolevulinic Acid use facilitates the extend of resection in case of high-grade gliomas, especially when differentiating normal brain from tumor periphery is challenging.
Methods |
Complete resection of glioblastoma via a supraorbital transciliary approach with 5-Aminolevulinic Acid use was performed without any complications, as demonstrated on postoperative MRI.
Results |
Patient was discharged on the third postoperative day. Wound follow-up shows good cosmetic result. Patient underwent concomitant chemo-radiation (Temozolomide- 60Gy) and adjuvant chemotherapy (Temozolomide). No tumor recurrence was noted at six months follow-up.
Conclusion |
In selected cases, supraorbital transciliary approach could be proposed as primary approach as it provides the advantage of full control over all the vasculo-nervous structures at skull base without the necessity of protective brain retractor use while the 5-Aminolevulinic Acid use allows a gross total resection.
Le texte complet de cet article est disponible en PDF.Keywords : Case report, Transciliary supraorbital approach, Glioma, Skull base, Surgical technique, 5Aminolevulinic Acid use
Plan
Vol 69 - N° 1
Article 101387- janvier 2023 Retour au numéro
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