Dissociative experiences like trance or depersonalisation may play a prominent role in pathological skin picking (PSP). However, trait and state dissociation and their relation to skin picking have hardly been studied in those with PSP. By means of an anonymous online survey, we recruited 323 adults with PSP defined by Skin Picking Scale-Revised (SPS-R) scores ≥ 7 as well as Skin Picking Impact Scale (SPIS) scores ≥ 7. Participants were administered the Dissociative Experiences Scale-Taxon (DES-T) to determine trait dissociation as well as the modified Peritraumatic Dissociative Experiences Questionnaire (PDEQ) to assess state dissociation during a typical episode of PSP. Sixty-three participants (19.5%) were assigned to the pathological dissociative taxon, that is, were high in trait dissociation. State dissociation during episodes of skin picking was reported by 221 individuals (68.4%) with the feeling of being on “automatic pilot” (49.6%) and alterations in time perception (33.1%) being the most frequent phenomena. Both trait and state dissociation were significantly associated with skin picking-related impairment, but effect sizes were small. Dissociation conceived as trait and state might be an important psychopathological dimension in skin picking. Its systematic detection and recognition may hold therapeutic implications as dissociation is a negative predictor of treatment outcome.