Impact of timing of delivery for type 2 diabetes on perinatal outcomes - 19/01/24
, Akshaya Kannan b, Nasim C. Sobhani b
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Highlights |
• | Compared to full term delivery, early term delivery for T2DM is associated with higher NICU admission rate. |
• | Delivery timing at early term versus full term had no significant impact on maternal outcomes. |
• | Early term delivery for the indication of T2DM may worsen neonatal outcomes. |
Abstract |
Aims |
To compare obstetric and neonatal outcomes in patients with type 2 diabetes mellitus (T2DM) who had scheduled delivery at full term (≥ 39 0/7 weeks) compared to early term (37 0/7 – 38 6/7 weeks) for T2DM indications.
Methods |
This was a retrospective cohort study that included all singletons with T2DM with a scheduled delivery at a single tertiary care center between January 2008 and March 2022. Outcomes were compared using Fisher's exact test.
Results |
107 singleton pregnancies were included. There was no significant difference in primary cesarean delivery between the two groups. The early term group had significantly higher rates of NICU admission compared to the term group (52% vs 32%, p = 0.05, OR 2.3, 95% CI 1.0–5.0), a finding that remained statistically significant on adjusted analysis (adjusted OR 2.81, 95% CI 1.04–7.58).
Conclusions |
In singleton pregnancies undergoing scheduled delivery for T2DM-specific indications, early term deliveries were associated with significantly increased odds of NICU admission when compared to term deliveries, even after adjusting for surrogate markers of glycemic control. These findings suggest that early term delivery contributes to risk of NICU admission, rather than the indication for delivery itself. These findings should be replicated in a larger cohort.
Le texte complet de cet article est disponible en PDF.Keywords : Diabetes in pregnancy, T2DM, Neonatal outcomes, NICU, Early term, Delivery timing
Plan
| This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Declarations of interest: none. |
Vol 14
Article 100196- avril 2024 Retour au numéro
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