Prevalence of major embolic findings and incidental findings on early cardiac CT in patients with suspected ischemic stroke - 01/09/24
Highlights |
• | Cardioembolic origin is one of the leading cause of ischemic stroke. |
• | Cardiac CT helps early detect conditions that put patients at risk of stroke. |
• | Looking beyond the heart in the search for incidental findings on cardiac CT can have a major clinical impact. |
Abstract |
Purpose |
The purpose of this study was to assess the type and prevalence of stroke and non-stroke-related findings diagnosed on early cardiac computed tomography (CT) in patients with suspected stroke. The secondary objective was to assess the clinical consequences on the management of patients with non-stroke-related conditions identified by early cardiac CT.
Materials and methods |
This single-center, retrospective, observational study included 1111 consecutive patients with suspected ischemic stroke between November 2018 and March 2020 who underwent cardiac CT examination in addition to the usual brain CT protocol (i.e., non-enhanced brain CT, perfusion brain CT when needed, aortic arch and supra-aortic CT angiography, and post contrast brain CT). There were 562 women and 549 men with a median age of 74 years (range: 60–85 years). Of these, 415 (415/1111; 37.4%) patients had ischemic stroke and 692 (692/1111; 62.3%) had no stroke. Cardiac CT examinations were retrospectively reviewed for cardiac CT findings at high embolic risk and clinically significant extracardiac incidental findings.
Results |
Among 1111 included patients, 89 (89/1111; 8.0%) had a stroke-related condition identified on early cardiac CT. This was significantly more frequent in patients with ischemic stroke (66/415; 15.9%) by comparison with those without ischemic stroke (23/696; 3.3%) (P < 0.001), with 41 patients (41/415; 9.9%) diagnosed with left atrial thrombus. Cardiac CT revealed a clinically significant non-stroke-related finding in 173 patients (173/1111; 15.6%), including 17 pulmonary embolisms (1.5%), seven suspicious pulmonary lesions (0.6%), and three breast lesions suspected to be malignant (0.3%). Twenty out of 173 patients (20/173; 11.5%) with incidental findings on early cardiac CT had a change in their management.
Conclusion |
This study shows that adding early cardiac CT to brain CT during the acute phase of an ischemic stroke leads to a higher rate of etiological diagnoses and highlights the major interest of looking at the bigger picture.
Le texte complet de cet article est disponible en PDF.Keywords : Cardiac CT, Computed tomography angiography, Incidentaloma, Ischemic stroke, Thrombosis
Abbreviations : AiCE, CT, CCTA, ECG, LAA, LAAT, MRI, PE, TE
Plan
Vol 105 - N° 9
P. 336-343 - septembre 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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